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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b764f53ed94d5f0d1ff02f969b56e7706d8f4b6d90b1ed9cbff4c26d3ff42801' 
  AND token = 'VXKmYYET68sdXj0QygpbAr6br+1rGc4k9Jf+3lyHkCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}