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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c88920123e2ac09cb9339bc514a0a48f10edeea010fb50e7ab0913d1009ede7' 
  AND token = 'JcAHeFVVxWoKdHVnAE6DKV7r5nKDaEtUM8/409NrGFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}