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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '780b6bba690570d56b24b1d40a6966469175f9d57762fbf2e2441277c00bb44b' 
  AND token = 'NFcssfG9qYWawAzMlt0nfwvXaiiLkorSXcv0KlJ5F+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}