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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b40c5a64329d0a55e5d805c24aa66d24d641003dedbc77dd75cb21a4b3084a' 
  AND token = 'PN0grWhM8hgOXgTPpOhYImcYTof5MIEqWKq8qy+PBPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}