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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3f97aaa3338657f2362817f3d1f77b9e962a91f262c2384fdd845f31e9b1019' 
  AND token = 'otN7Iz7MXRMU+pxa01NTLk/1ZITrsMVX0qCPE96lnP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}