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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '987e32a75545a308fdf8f457831c6b8449c7e18b8e7d366f37c321f30cb8ee5d' 
  AND token = 'wxwRE6IcqeyCZ9PZMUOTV08hgHmjfWdb0LsRMa+sM+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}