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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9efbc8301a7913c572bda75cd124c9b1c316248ea6761f767afe7bfb5667f61e' 
  AND token = 'IZ5Kl/hIDh16aOkvOdkKCF282AYe40tAi9yxvAIRnWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}