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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c041816cc5b84cb50af56a81b91b41d71d508bd21905d8b985c8edb7afa2ba3' 
  AND token = '8SYM0jq8jfnav/zGBuGiAtze0To3DM3AYEjNP7ioVxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}