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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0356681638c6b7eb3a259dceb54b1a7e300dfcf639c9df4ed4df8ca1581bd893' 
  AND token = 'FzfXMLARDHZTZfHv05nlWi9mpbzGNeF/s5Ng3A42c7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}