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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd12c0189cf5b22cb727f27b34047cd30053a65bb2b39c975da917ddcce667304' 
  AND token = 'wqiOD6x8V44hL7+Nznk2rJbzePx5kT42yFZMJDXNins=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}