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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39f219e7dddaace28be7a4ac39c43d7776a657d8b472e7a42df92a3f93629a51' 
  AND token = 'aR08JHVS1ZhUpM2uanGO4sVc4VBt7tcuv1112jwXfvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}