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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29cca81c20a3b63e72482caab11649debf008d590385b98346d8abadb921f888' 
  AND token = 'z1YE1jfty/UCbV9cSID0lyL6348ukhawOPe0/UoEY8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}