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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08c90a18d58834586b8e8c1edab2e4be25d06dc569e2b07a321ebe21ffd43ec7' 
  AND token = '6//u06fBHFFkXuYaUI/puZkH4R0wRg8uvWp3nfr7EiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}