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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4c5853b2658cc3360f66112a56e52db36f8399b427f09e634510400c2d44180' 
  AND token = 'QflHfdYaOW7mCK0CYkKC1oGMLkN+bxwmla81KsZgQCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}