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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd799d1c483ca27be01dd82504a10e1000f278df4d9ff60e0cecf70d28a4e1f63' 
  AND token = '6HPfr8An8P6cwmV101zkzQO3APDLXxA8lNRjjpxcDNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}