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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c2b7c121204acec1d6c0b85c281abe1694a721cc9005492d95696ee7e164bab' 
  AND token = 'YyGDW5pyCDG8vPe/2mUT2gRwulVNy8Ux6U86x46ZziY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}