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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5f383a8c54c1d95ee02df6eeea06224e0426fcb45d04f0beeb513ebdce687a1' 
  AND token = '8Gb7YvkI50yHOU3w61weWvt2LHckdKBN0bGT3yova2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}