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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf5da05832e62b96ca28e7ebcc42cfa557661f663cb3adad273c7dd01c527595' 
  AND token = 'Ycl+hcpAJeek6MhiJF9z+iCSQM6Ha/TrIPPs5vWhFqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}