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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f89996791c7cbc57f8d1966a60fa72a9a75a528231ba52e05b8b225b944be593' 
  AND token = 'TGFnaL9BaQddGzMTceSYjvyJG6ZMxqzfkyY1l9FjGhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}