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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a60761a7176e08396f99f8fa0ed2e5931f2861de68e4d24cdbee20046f70d3c' 
  AND token = 'i2inWZXWE/4p5THpoj7CigWGlVUBRanRZuCszTY/M74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}