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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e451f392bcfde8894f4fb56b9b25db4b4e14dde94981ee0ca0cdada28369892' 
  AND token = 'm1NtCe10qfWiMViE03E5X0Y43A74J710wk622vi/ZQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}