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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed604843ec6f097212d66240f44d5fa4f5d7146d8e8698e54eec4b1b67cee4e4' 
  AND token = 'sGDPVIT7lveTVOist3bvS7hO0f1Y0l5Ie6ZBGtzvFwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}