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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4052e6817b97d60ca2f7299b626a32cab44444fa9b4aad1b6de9798d7fcd814' 
  AND token = 'YNydw32k7obV92O6EyWpmML49qs0JyQI11vQVD5lEgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}