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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bd3e28c822b6bdc56066cded43168dfb60d8fd86344dfd26e85e1e29c6df6f0' 
  AND token = '4DJLr5zhuhe+8/pGz7yNrSt3t6LPn4eYOhDuvJZAS8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}