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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35d64af8eb5f89279415430b1cc2c330fc653757afac93a9059c8624c5c98806' 
  AND token = '4bx2LM9kfSsk5CaO8IQJSdJdXEHYhxGsfBH+nZGwCf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}