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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '759c78d0e8ff2a63c8fd1d0a1657b9e74082379078a988f804704f1234fa1787' 
  AND token = 'ho7u1qrfXv+soZUs7e8beUaSRNJjxsnU8qk1KgGg1yE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}