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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ddf7fb87d08f1dbc17f57afa1b7b547385bb6faef5f8d1f593f241c10e41891' 
  AND token = 'enxNJQO8J7lonvvFwwG2kgmiQq1IbxKWcIcyeu2ROpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}