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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6264b6a16b20b3683c72fa0bd3f441c6085ac24ede54c35414eda4d66c4245' 
  AND token = 'tni1GpdOW9ufK/yGfw3uJSqykBLs4rbt1tOd0mohDms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}