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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db1cdec8c7ad172c022dc8ea68bd8eefe23e0eb0e8bc49c5835234c250deb824' 
  AND token = 'Ar1MabxEF6APzjEbG5m0nbQN6yshdLK2nfipvOQe6Xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}