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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e85cb89b6dbae36cf8c679ce8d57f9d98f8c046b47e50d3a2dcff99a96f0aee9' 
  AND token = '78diFg6+AgAVB5Mzm+k6j1oUEoZKStUit25kmhjFXfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}