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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d18dba21cfb42ba5867eb43b1440578ec61dc811d888f148aa76ea70b1c9c64' 
  AND token = 'fcIwzb4joxqjiYXP23d2hrRX8DAam4Sh0k0Kl81KJU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}