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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1484f77c7ed375255f8001e312b230d1e3a0fd13a80da6e2f7879cfb8db387f' 
  AND token = '3eAXWrsO6/kzcjpK6h04LiKebe7P37aLPcOX/sw+JQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}