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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb72868dbaf44fca6aed9ff893be9e9d233d03a49274e047ea42f8c78ae94948' 
  AND token = 'VS7FKT4I0tCQJfsB7XqbFmOjT34zVsgZveYHKSambrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}