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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44700aa5fab739f040bb6b88197e615654991563d0620a4351c9a36a24116ff0' 
  AND token = 'XmwgImY7biL1S5suOXIqa7L9a9OQ77WQryh69nDbnUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}