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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387d16b534c69b0b5b50140594f54551a3486d11098a9cb234e50e37bce43b3c' 
  AND token = 'SZhrSjU5Efqbmg4fJBH1RiAcGh+9DOXOdcIicnSvpWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}