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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d3aca65f250cb583f89b428512f695b780d4d3eb860c6471a363c8d151a92c6' 
  AND token = 'Wgq4p4Dzyz95iZtDzP996m3tUIugcDORqNAeMe1+Xj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}