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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a270aee73391f54e703e4a475ce4cd24b814924d9ed4cbd5541a0fa650ac1c45' 
  AND token = '8sNz4kTFLCZtnV3mabXt1D19RkiT5MwEVBTZWvjwlTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}