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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ccde0398cd82a535c5db15e3bb687bd21ada9079a9c3acaa142ef56e54b6b9c' 
  AND token = 'uh5Vg9xqZs+SRmZVpV/Gzs74H0yNszhvPva4oRliAV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}