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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97b3c781ac7be5523434bcdaa94f31e94d7b6de1b7d9a4d127784f49a8e4352f' 
  AND token = '3rYFdyZkRO72+U46LH8lo6/osmppCCAxcgxeMnRIZXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}