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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86c4948cd61f2b35743e3861d16a5705baa3989f8246cfcd98c5e09a728e4fd7' 
  AND token = 'LoGFMAGRgAWB00g4C/azOeQWN1G1LJfBha+L5CfGOIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}