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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e9c0d28cd67a493ee23880c2cf4031b6b3156914237f5e587317248e3ad437d' 
  AND token = 'IHFkoxYIAD3Ji0A38m2ykLUNT2RAHHWqxnYcGzannLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}