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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '361215a8a71c8351a09c867d21b26d76ddfc55e9e82dda73bb92939c3a15716c' 
  AND token = 'syPHNw9Ws2raxUxozyFWCJHlyCtB22XbeYy/YZCF9Ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}