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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8c9a234e996566e36850523a256d269d621d3303deb08ecf7bbfe332393b510' 
  AND token = '/U76yCEh5egc0YMQ3MUcvy4TbLr8/LosNhL6VQvbfkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}