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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9488f1ee266efbce69cd53cf0b2edf3d76ddd19d1824a12f0170e491ed496c21' 
  AND token = 'Fl7QTLwLsv5Lyi5peEZ3gYw2PMWt0x+XOtmBsYfWSkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}