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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed4172688baee6f52d4b288fea9ab251f0b39ccf39cea2fc76f219846989eae3' 
  AND token = 'Fa47de4V0rV+2T3R0zDkHXrJNhfGPIwVgQ/Ddn5IuSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}