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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75ecb7c5a918560bbf453289a4e4e6a1ae0b7cb5081bbb14d7d54d76c0f783bc' 
  AND token = 'EPPc/c8UW9O5sgyB4VDJTRJhRRJkcDpEHQkQ9aCb6qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}