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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f01d041dacae1d09d532312497f5394b9c65dbc02f77395dd98f000450a60450' 
  AND token = 'aeeQtpHo1qnHD3mWvOG8aU7mX4ZNzYUkd4JootWjdzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}