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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4cbf3221893af7c090990011e99e48f8ee64279f1c504e79d97335dd46dbb20' 
  AND token = '7Xt64SNSAV3FH4Ogf74/HGRMvR83x3Znqm7yxWhVUIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}