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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '143aa429198fa957d1032e47395237fe2ce1165e67e48d344b8865d760b4f11e' 
  AND token = '/3xAXU4DVVQuuMochCOFa1E9vqk2e86j1yS0IIGWdvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}