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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7c3d2381ed102b297bd564e1ccfb84354225ef9ca59686cbe1e548ea7d8019d' 
  AND token = 'b5M6XYmJzP8PtStXu49mkf1cwzMFmXe3K+hbTmDDQ2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}